Prion Strain Differences in Accumulation of PrPSc on Neurons and Glia Are Associated with Similar Expression Profiles of Neuroinflammatory Genes: Comparison of Three Prion Strains

Misfolding and aggregation of host proteins are important features of the pathogenesis of neurodegenerative diseases including Alzheimer’s disease, Parkinson’s disease, frontotemporal dementia and prion diseases. In all these diseases, the misfolded protein increases in amount by a mechanism involvi...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS Pathog
Main Authors: Carroll, James A., Striebel, James F., Rangel, Alejandra, Woods, Tyson, Phillips, Katie, Peterson, Karin E., Race, Brent, Chesebro, Bruce
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821575/
https://ncbi.nlm.nih.gov/pubmed/27046083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005551
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki