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Early Generation of New PrPSc on Blood Vessels after Brain Microinjection of Scrapie in Mice

Aggregation of misfolded host proteins in the central nervous system is believed to be important in the pathogenic process in several neurodegenerative diseases of humans, including prion diseases, Alzheimer’s disease, and Parkinson’s disease. In these diseases, protein misfolding and aggregation ap...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Chesebro, Bruce, Striebel, James, Rangel, Alejandra, Phillips, Katie, Hughson, Andrew, Caughey, Byron, Race, Brent
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600122/
https://ncbi.nlm.nih.gov/pubmed/26396245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01419-15
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