Early Generation of New PrPSc on Blood Vessels after Brain Microinjection of Scrapie in Mice

Aggregation of misfolded host proteins in the central nervous system is believed to be important in the pathogenic process in several neurodegenerative diseases of humans, including prion diseases, Alzheimer’s disease, and Parkinson’s disease. In these diseases, protein misfolding and aggregation ap...

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Bibliografske podrobnosti
izdano v:mBio
Main Authors: Chesebro, Bruce, Striebel, James, Rangel, Alejandra, Phillips, Katie, Hughson, Andrew, Caughey, Byron, Race, Brent
Format: Artigo
Jezik:Inglês
Izdano: American Society of Microbiology 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600122/
https://ncbi.nlm.nih.gov/pubmed/26396245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01419-15
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