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Phosphorylation of the amino-terminus of the AGC kinase Gad8 prevents its interaction with TORC2

Cell proliferation, metabolism, migration and survival are coordinated through the tight control of two target of rapamycin (TOR) kinase complexes: TORC1 and TORC2. Here, we show that a novel phosphorylation of fission yeast Gad8 (AGC kinase) on the evolutionarily conserved threonine 6 (Thr6) preven...

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書目詳細資料
發表在:Open Biol
Main Authors: Du, Wei, Forte, Gabriella M., Smith, Duncan, Petersen, Janni
格式: Artigo
語言:Inglês
出版: The Royal Society 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821236/
https://ncbi.nlm.nih.gov/pubmed/26935949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.150189
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