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Phosphorylation of the amino-terminus of the AGC kinase Gad8 prevents its interaction with TORC2

Cell proliferation, metabolism, migration and survival are coordinated through the tight control of two target of rapamycin (TOR) kinase complexes: TORC1 and TORC2. Here, we show that a novel phosphorylation of fission yeast Gad8 (AGC kinase) on the evolutionarily conserved threonine 6 (Thr6) preven...

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Detalhes bibliográficos
Publicado no:Open Biol
Main Authors: Du, Wei, Forte, Gabriella M., Smith, Duncan, Petersen, Janni
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821236/
https://ncbi.nlm.nih.gov/pubmed/26935949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.150189
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