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Early afterdepolarizations promote transmural reentry in ischemic human ventricles with reduced repolarization reserve

AIMS: Acute ischemia is a major cause of sudden arrhythmic death, further promoted by potassium current blockers. Macro-reentry around the ischemic region and early afterdepolarizations (EADs) caused by electrotonic current have been suggested as potential mechanisms in animal and isolated cell stud...

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Detalhes bibliográficos
Publicado no:Prog Biophys Mol Biol
Main Authors: Dutta, Sara, Mincholé, Ana, Zacur, Ernesto, Quinn, T. Alexander, Taggart, Peter, Rodriguez, Blanca
Formato: Artigo
Idioma:Inglês
Publicado em: Pergamon Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821233/
https://ncbi.nlm.nih.gov/pubmed/26850675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbiomolbio.2016.01.008
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