Glandular Proteome Identifies Antiprotease Cystatin C as a Critical Modulator of Airway Hydration and Clearance

Defects in the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel lead to viscous secretions from submucosal glands that cannot be properly hydrated and cleared by beating cilia in cystic fibrosis (CF) airways. The mechanisms by which CFTR, and the predominant epithelial sod...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Am J Respir Cell Mol Biol
मुख्य लेखकों: Evans, T. Idil Apak, Joo, Nam Soo, Keiser, Nicholas W., Yan, Ziying, Tyler, Scott R., Xie, Weiliang, Zhang, Yulong, Hsiao, Jordy J., Cho, Hyung-Ju, Wright, Michael E., Wine, Jeffrey J., Engelhardt, John F.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Thoracic Society 2016
विषय:
Original Research
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821051/
https://ncbi.nlm.nih.gov/pubmed/26334941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0090OC
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