Urban Particulate Matter–Activated Human Dendritic Cells Induce the Expansion of Potent Inflammatory Th1, Th2, and Th17 Effector Cells

Exposure to urban particulate matter (UPM) exacerbates asthmatic lung inflammation. Lung dendritic cells (DCs) are critical for stimulating T cell immunity and in maintaining airway tolerance, but they also react to airway UPM. The adjuvant role of UPM in enhancing primary immune responses by naive...

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Опубликовано в: :Am J Respir Cell Mol Biol
Главные авторы: Matthews, Nick C., Pfeffer, Paul E., Mann, Elizabeth H., Kelly, Frank J., Corrigan, Christopher J., Hawrylowicz, Catherine M., Lee, Tak H.
Формат: Artigo
Язык:Inglês
Опубликовано: American Thoracic Society 2016
Предметы:
Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821044/
https://ncbi.nlm.nih.gov/pubmed/26196219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0084OC
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