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Aberrant DNA Methylation of Phosphodiestarase 4D Alters Airway Smooth Muscle Cell Phenotypes
Airway hyperresponsiveness (AHR) is a hallmark feature in asthma characterized by exaggerated airway contractile response to stimuli due to increased airway sensitivity and chronic airway remodeling. We have previously shown that allergen-induced AHR in mice is associated with aberrant DNA methylati...
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| Izdano u: | Am J Respir Cell Mol Biol |
|---|---|
| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Thoracic Society
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4821043/ https://ncbi.nlm.nih.gov/pubmed/26181301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0079OC |
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