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Novel Inhibitory Effect of a Lysophosphatidic Acid 2 Agonist on Allergen-Driven Airway Inflammation
Lysophosphatidic acid (LPA) is a pleiotropic lipid signaling molecule associated with asthma pathobiology. LPA elicits its effects by binding to at least six known cell surface G protein–coupled receptors (LPA(1–6)) that are expressed in the lung in a cell type–specific manner. LPA(2) in particular...
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| Vydáno v: | Am J Respir Cell Mol Biol |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Thoracic Society
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4821034/ https://ncbi.nlm.nih.gov/pubmed/26248018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0124OC |
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