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Novel Inhibitory Effect of a Lysophosphatidic Acid 2 Agonist on Allergen-Driven Airway Inflammation

Lysophosphatidic acid (LPA) is a pleiotropic lipid signaling molecule associated with asthma pathobiology. LPA elicits its effects by binding to at least six known cell surface G protein–coupled receptors (LPA(1–6)) that are expressed in the lung in a cell type–specific manner. LPA(2) in particular...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Knowlden, Sara A., Hillman, Sara E., Chapman, Timothy J., Patil, Renukadevi, Miller, Duane D., Tigyi, Gabor, Georas, Steve N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821034/
https://ncbi.nlm.nih.gov/pubmed/26248018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0124OC
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