Mesangial cells from patients with IgA nephropathy have increased susceptibility to galactose-deficient IgA1

BACKGROUND: IgA nephropathy (IgAN) is the most common glomerulonephritis in the world, affecting close to a million people. Circulating galactose-deficient IgA (gd-IgA), present in patients with IgAN, form immune complex deposits in the glomerular mesangium causing local proliferation and matrix exp...

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Dettagli Bibliografici
Pubblicato in:BMC Nephrol
Autori principali: Ebefors, Kerstin, Liu, Peidi, Lassén, Emelie, Elvin, Johannes, Candemark, Emma, Levan, Kristina, Haraldsson, Börje, Nyström, Jenny
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820936/
https://ncbi.nlm.nih.gov/pubmed/27044423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-016-0251-5
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