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Population pharmacokinetic analysis and dosing regimen optimization of penicillin G in patients with infective endocarditis

BACKGROUND: This study was designed to evaluate the population pharmacokinetics (popPK) of penicillin G in patients with infective endocarditis and establish a dosage regimen based on pharmacokinetic data and clinical outcome. METHOD: Forty-six serum penicillin G samples from 25 individuals were ana...

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Publicat a:J Pharm Health Care Sci
Autors principals: Komatsu, Toshiaki, Inomata, Takayuki, Watanabe, Ichiro, Kobayashi, Masahiro, Kokubun, Hideya, Ako, Junya, Atsuda, Koichiro
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820900/
https://ncbi.nlm.nih.gov/pubmed/27051524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40780-016-0043-x
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