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Bidirectional regulation of synaptic transmission by BRAG1/IQSEC2 and its requirement in long-term depression

Dysfunction of the proteins regulating synaptic function can cause synaptic plasticity imbalance that underlies neurological disorders such as intellectual disability. A study found that four distinct mutations within BRAG1, an Arf-GEF synaptic protein, each led to X-chromosome-linked intellectual d...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Brown, Joshua C., Petersen, Amber, Zhong, Ling, Himelright, Miranda L., Murphy, Jessica A., Walikonis, Randall S., Gerges, Nashaat Z.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820844/
https://ncbi.nlm.nih.gov/pubmed/27009485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11080
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