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Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells
Aged haematopoietic stem cells (HSCs) generate more myeloid cells and fewer lymphoid cells compared with young HSCs, contributing to decreased adaptive immunity in aged individuals. However, it is not known how intrinsic changes to HSCs and shifts in the balance between biased HSC subsets each contr...
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| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4820843/ https://ncbi.nlm.nih.gov/pubmed/27009448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11075 |
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