Specific interference shRNA-expressing plasmids inhibit Hantaan virus infection in vitro and in vivo

AIM: To investigate the antiviral effects of vectors expressing specific short hairpin RNAs (shRNAs) against Hantaan virus (HTNV) infection in vitro and in vivo. METHODS: Based on the effects of 4 shRNAs targeting different regions of HTNV genomic RNA on viral replication, the most effective RNA int...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Liu, Yuan-yuan, Chen, Liang-jun, Zhong, Yan, Shen, Meng-xin, Ma, Nian, Liu, Bing-yu, Luo, Fan, Hou, Wei, Yang, Zhan-qiu, Xiong, Hai-rong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820803/
https://ncbi.nlm.nih.gov/pubmed/26972493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.165
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