Altered Glycolysis and Mitochondrial Respiration in a Zebrafish Model of Dravet Syndrome123

Altered metabolism is an important feature of many epileptic syndromes but has not been reported in Dravet syndrome (DS), a catastrophic childhood epilepsy associated with mutations in a voltage-activated sodium channel, Nav1.1 (SCN1A). To address this, we developed novel methodology to assess real-...

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Publicat a:eNeuro
Autors principals: Kumar, Maneesh G., Rowley, Shane, Fulton, Ruth, Dinday, Matthew T., Baraban, Scott C., Patel, Manisha
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2016
Matèries:
New Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820792/
https://ncbi.nlm.nih.gov/pubmed/27066534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0008-16.2016
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