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Synthesis of Rumphellaone A and Hushinone by a Gold-Catalyzed [2 + 2] Cycloaddition

[Image: see text] The enantioselective total synthesis of rumphellaone A has been accomplished in 12 steps via a diastereoselective gold(I)-catalyzed [2 + 2] macrocyclization of a 1,10-enyne as the key step to build the cyclobutene moiety. This concise approach has also led to the total synthesis of...

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Detaylı Bibliyografya
Yayımlandı:Org Lett
Asıl Yazarlar: Ranieri, Beatrice, Obradors, Carla, Mato, Mauro, Echavarren, Antonio M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2016
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820790/
https://ncbi.nlm.nih.gov/pubmed/26974011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.6b00473
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