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Cleaning out the Litterbox of Proteomic Scientists’ Favorite Pet: Optimized Data Analysis Avoiding Trypsin Artifacts

[Image: see text] Chemically modified trypsin is a standard reagent in proteomics experiments but is usually not considered in database searches. Modification of trypsin is supposed to protect the protease against autolysis and the resulting loss of activity. Here, we show that modified trypsin is s...

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Detaylı Bibliyografya
Yayımlandı:J Proteome Res
Asıl Yazarlar: Schittmayer, Matthias, Fritz, Katarina, Liesinger, Laura, Griss, Johannes, Birner-Gruenberger, Ruth
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2016
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820788/
https://ncbi.nlm.nih.gov/pubmed/26938934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.5b01105
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