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Tetrahydroanthraquinone Derivative (±)-4-Deoxyaustrocortilutein Induces Cell Cycle Arrest and Apoptosis in Melanoma Cells via Upregulation of p21 and p53 and Downregulation of NF-kappaB

Background: Malignant melanoma is an aggressive type of skin cancer with high risk for metastasis and chemoresistance. Disruption of tightly regulated processes such as cell cycle, cell adhesion, cell differentiation and cell death are predominant in melanoma development. So far, conventional treatm...

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Detalhes bibliográficos
Publicado no:J Cancer
Main Authors: Genov, Miroslav, Kreiseder, Birgit, Nagl, Michael, Drucker, Elisabeth, Wiederstein, Martina, Muellauer, Barbara, Krebs, Julia, Grohmann, Teresa, Pretsch, Dagmar, Baumann, Karl, Bacher, Markus, Pretsch, Alexander, Wiesner, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820732/
https://ncbi.nlm.nih.gov/pubmed/27053954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.13614
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