Tetrahydroanthraquinone Derivative (±)-4-Deoxyaustrocortilutein Induces Cell Cycle Arrest and Apoptosis in Melanoma Cells via Upregulation of p21 and p53 and Downregulation of NF-kappaB

Background: Malignant melanoma is an aggressive type of skin cancer with high risk for metastasis and chemoresistance. Disruption of tightly regulated processes such as cell cycle, cell adhesion, cell differentiation and cell death are predominant in melanoma development. So far, conventional treatm...

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Publicat a:J Cancer
Autors principals: Genov, Miroslav, Kreiseder, Birgit, Nagl, Michael, Drucker, Elisabeth, Wiederstein, Martina, Muellauer, Barbara, Krebs, Julia, Grohmann, Teresa, Pretsch, Dagmar, Baumann, Karl, Bacher, Markus, Pretsch, Alexander, Wiesner, Christoph
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820732/
https://ncbi.nlm.nih.gov/pubmed/27053954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.13614
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