Structure of the full-length TRPV2 channel by cryo-EM

Transient receptor potential (TRP) proteins form a superfamily Ca(2+)-permeable cation channels regulated by a range of chemical and physical stimuli. Structural analysis of a ‘minimal' TRP vanilloid subtype 1 (TRPV1) elucidated a mechanism of channel activation by agonists through changes in i...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Huynh, Kevin W., Cohen, Matthew R., Jiang, Jiansen, Samanta, Amrita, Lodowski, David T., Zhou, Z. Hong, Moiseenkova-Bell, Vera Y.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820614/
https://ncbi.nlm.nih.gov/pubmed/27021073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11130
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