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Application of amphipols for structure-functional analysis of TRP channels
Amphipathic polymers (amphipols), such as A8-35 and SApol, are a new tool for stabilizing integral membrane proteins in detergent-free conditions for structural and functional studies. Transient receptor potential (TRP) ion channels function as tetrameric protein complexes in a diverse range of cell...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4198461/ https://ncbi.nlm.nih.gov/pubmed/24894720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00232-014-9684-6 |
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