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Targeting of hexokinase 1 to liver and hepatoma mitochondria.

The proportion of hexokinase (HK; EC 2.7.1.1) isozyme 1 (HK1) that is bound to the outer mitochondrial membrane is tissue specific and developmentally regulated. HK activity is known to be markedly elevated in many cancer cells and a significant fraction is mitochondrial bound. This study examined t...

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Detalhes bibliográficos
Main Authors: Gelb, B D, Adams, V, Jones, S N, Griffin, L D, MacGregor, G R, McCabe, E R
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC48204/
https://ncbi.nlm.nih.gov/pubmed/1309605
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