Template-dependent nucleotide addition in the reverse (3′-5′) direction by Thg1-like protein

Thg1-like protein (TLP) catalyzes the addition of a nucleotide to the 5′-end of truncated transfer RNA (tRNA) species in a Watson-Crick template–dependent manner. The reaction proceeds in two steps: the activation of the 5′-end by adenosine 5′-triphosphate (ATP)/guanosine 5′-triphosphate (GTP), foll...

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Udgivet i:Sci Adv
Main Authors: Kimura, Shoko, Suzuki, Tateki, Chen, Meirong, Kato, Koji, Yu, Jian, Nakamura, Akiyoshi, Tanaka, Isao, Yao, Min
Format: Artigo
Sprog:Inglês
Udgivet: American Association for the Advancement of Science 2016
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820378/
https://ncbi.nlm.nih.gov/pubmed/27051866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1501397
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