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The EGFR-HER2 module: a stem cell approach to understanding a prime target and driver of solid tumors

The epidermal growth factor receptor (EGFR) and a co-receptor denoted HER2/ERBB2, are frequently overexpressed or mutated in solid tumors, such as carcinomas and gliomas. In line with driver roles, cancer drugs intercepting EGFR or HER2 currently outnumber therapies targeting other hubs of signal tr...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Schneider, Marlon R., Yarden, Yosef
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820040/
https://ncbi.nlm.nih.gov/pubmed/26434585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.372
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