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Histone modification profiling reveals differential signatures associated with human embryonic stem cell self-renewal and differentiation

In this study, we trace developmental stages using epigenome changes in human embryonic stem cells (hESCs) treated with drugs modulating either self-renewal or differentiation. Based on microscopy, qPCR and flow cytometry, we classified the treatment outcome as inducing pluripotency (hESC, flurbipro...

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Detalhes bibliográficos
Publicado no:Proteomics
Main Authors: Bhanu, Natarajan V., Sidoli, Simone, Garcia, Benjamin A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4819991/
https://ncbi.nlm.nih.gov/pubmed/26631989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201500231
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