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The Chemical Biology of Human Metallo-β-Lactamase Fold Proteins
The αββα metallo β-lactamase (MBL) fold (MBLf) was first observed in bacterial enzymes that catalyze the hydrolysis of almost all β-lactam antibiotics, but is now known to be widely distributed. The MBL core protein fold is present in human enzymes with diverse biological roles, including cell detox...
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| Veröffentlicht in: | Trends Biochem Sci |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier Trends Journals
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4819959/ https://ncbi.nlm.nih.gov/pubmed/26805042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2015.12.007 |
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