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Polycystin-1, the PKD1 gene product, is in a complex containing E-cadherin and the catenins

Autosomal dominant polycystic kidney disease (ADPKD) is a common human genetic disease characterized by cyst formation in kidney tubules and other ductular epithelia. Cells lining the cysts have abnormalities in cell proliferation and cell polarity. The majority of ADPKD cases are caused by mutation...

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Detalhes bibliográficos
Main Authors: Huan, Yonghong, van Adelsberg, Janet
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC481982/
https://ncbi.nlm.nih.gov/pubmed/10562308
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