Increased expression of Solute carrier family 12 member 5 via gene amplification contributes to tumour progression and metastasis and associates with poor survival in colorectal cancer

OBJECTIVE: Using whole genome sequencing, we identified gene amplification of solute carrier family 12 member 5 (SLC12A5) located at 20q13.12 in colorectal cancer (CRC). We analysed its amplification, overexpression, biological effects and prognostic significance in CRC. DESIGN: SLC12A5 amplificatio...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Xu, Lixia, Li, Xiaoxing, Cai, Muyan, Chen, Jinna, Li, Xiangchun, Wu, William K K, Kang, Wei, Tong, Joanna, To, Ka-Fai, Guan, Xin-Yuan, Sung, Joseph J Y, Chan, Francis K L, Yu, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2016
Assuntos:
Colon
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4819609/
https://ncbi.nlm.nih.gov/pubmed/25947013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2014-308257
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