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Aberrant Hypomethylation of Solute Carrier Family 6 Member 12 Promoter Induces Metastasis of Ovarian Cancer

PURPOSE: Ovarian cancer (OC) is the most fatal of gynecological malignancies with a high rate of recurrence. We aimed to evaluate the expression of solute carrier family 6, member 12 (SLC6A12) and methylation of its promoter CpG sites in a xenograft mouse model of metastatic OC, and to investigate t...

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Publicat a:Yonsei Med J
Autors principals: Sung, Hye Youn, Yang, San-Duk, Park, Ae Kyung, Ju, Woong, Ahn, Jung-Hyuck
Format: Artigo
Idioma:Inglês
Publicat: Yonsei University College of Medicine 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122649/
https://ncbi.nlm.nih.gov/pubmed/27873492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3349/ymj.2017.58.1.27
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