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Toxicity Attribution in Phase I Trials: Evaluating the Effect of Dose on the Frequency of Related and Unrelated Toxicities
BACKGROUND: Phase I studies rely on investigators to accurately attribute of adverse events as related or unrelated to study drug. This information is ultimately used to help establish a safe dose. Patterns of physician attribution in the Phase I setting have not been widely studied and assessing th...
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| Wydane w: | Clin Cancer Res |
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| Główni autorzy: | , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2015
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4819316/ https://ncbi.nlm.nih.gov/pubmed/26324741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-0339 |
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