The Neuropsychiatric Disease-Associated Gene cacna1c Mediates Survival of Young Hippocampal Neurons123

Genetic variations in CACNA1C, which encodes the Ca(v)1.2 subunit of L-type calcium channels (LTCCs), are associated with multiple forms of neuropsychiatric disease that manifest high anxiety in patients. In parallel, mice harboring forebrain-specific conditional knockout of cacna1c (forebrain-Ca(v)...

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Detalhes bibliográficos
Publicado no:eNeuro
Main Authors: Lee, Anni S., De Jesús-Cortés, Héctor, Kabir, Zeeba D., Knobbe, Whitney, Orr, Madeline, Burgdorf, Caitlin, Huntington, Paula, McDaniel, Latisha, Britt, Jeremiah K., Hoffmann, Franz, Brat, Daniel J., Rajadhyaksha, Anjali M., Pieper, Andrew A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
Assuntos:
New Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4819284/
https://ncbi.nlm.nih.gov/pubmed/27066530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0006-16.2016
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