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Genetic background affects the expansion of macrophage subsets in the lungs of Mycobacterium tuberculosis‐infected hosts

M1 macrophages are more effective in the induction of the inflammatory response and clearance of Mycobacterium tuberculosis than M2 macrophages. Infected C57BL/6 mice generate a stronger cellular immune response compared with BALB/c mice. We hypothesized that infected C57BL/6 mice would exhibit a hi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Immunology
Hauptverfasser: Bertolini, Thais Barboza, de Souza, Alexandre Ignacio, Gembre, Ana Flávia, Piñeros, Annie Rocio, Prado, Rafael de Queiroz, Silva, João Santana, Ramalho, Leandra Naira Zambelli, Bonato, Vânia Luiza Deperon
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4819146/
https://ncbi.nlm.nih.gov/pubmed/26840507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12591
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