A Single Dose of a DNA Vaccine Encoding Apa Coencapsulated with 6,6′-Trehalose Dimycolate in Microspheres Confers Long-Term Protection against Tuberculosis in Mycobacterium bovis BCG-Primed Mice

Mycobacterium bovis BCG prime DNA (Mycobacterium tuberculosis genes)-booster vaccinations have been shown to induce greater protection against tuberculosis (TB) than BCG alone. This heterologous prime-boost strategy is perhaps the most realistic vaccination for the future of TB infection control, es...

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Detalhes bibliográficos
Main Authors: Carlétti, Dyego, Morais da Fonseca, Denise, Gembre, Ana Flávia, Masson, Ana Paula, Weijenborg Campos, Lívia, Leite, Luciana C. C., Rodrigues Pires, Andréa, Lannes-Vieira, Joseli, Lopes Silva, Célio, Bonato, Vânia Luiza Deperon, Horn, Cynthia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754502/
https://ncbi.nlm.nih.gov/pubmed/23740922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00148-13
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