Candidate SNP Markers of Gender-Biased Autoimmune Complications of Monogenic Diseases Are Predicted by a Significant Change in the Affinity of TATA-Binding Protein for Human Gene Promoters

Some variations of human genome [for example, single nucleotide polymorphisms (SNPs)] are markers of hereditary diseases and drug responses. Analysis of them can help to improve treatment. Computer-based analysis of millions of SNPs in the 1000 Genomes project makes a search for SNP markers more tar...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Ponomarenko, Mikhail P., Arkova, Olga, Rasskazov, Dmitry, Ponomarenko, Petr, Savinkova, Ludmila, Kolchanov, Nikolay
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4819121/
https://ncbi.nlm.nih.gov/pubmed/27092142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00130
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