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Contributions of DNA repair and damage response pathways to the non-linear genotoxic responses of alkylating agents
From a risk assessment perspective, DNA-reactive agents are conventionally assumed to have genotoxic risks at all exposure levels, thus applying a linear extrapolation for low-dose responses. New approaches discussed here, including more diverse and sensitive methods for assessing DNA damage and DNA...
में बचाया:
| में प्रकाशित: | Mutat Res Rev Mutat Res |
|---|---|
| मुख्य लेखकों: | , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2015
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4818947/ https://ncbi.nlm.nih.gov/pubmed/27036068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrrev.2015.11.001 |
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