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Reproducibility of Illumina platform deep sequencing errors allows accurate determination of DNA barcodes in cells

BACKGROUND: Next generation sequencing (NGS) of amplified DNA is a powerful tool to describe genetic heterogeneity within cell populations that can both be used to investigate the clonal structure of cell populations and to perform genetic lineage tracing. For applications in which both abundant and...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Beltman, Joost B., Urbanus, Jos, Velds, Arno, van Rooij, Nienke, Rohr, Jan C., Naik, Shalin H., Schumacher, Ton N.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818877/
https://ncbi.nlm.nih.gov/pubmed/27038897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-0999-4
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