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Small molecule inhibitors of the Dishevelled‐CXXC5 interaction are new drug candidates for bone anabolic osteoporosis therapy

Bone anabolic agents promoting bone formation and rebuilding damaged bones would ideally overcome the limitations of anti‐resorptive therapy, the current standard prescription for osteoporosis. However, the currently prescribed parathyroid hormone (PTH)‐based anabolic drugs present limitations and a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO Mol Med
Prif Awduron: Kim, Hyun‐Yi, Choi, Sehee, Yoon, Ji‐Hye, Lim, Hwan Jung, Lee, Hyuk, Choi, Jiwon, Ro, Eun Ji, Heo, Jung‐Nyoung, Lee, Weontae, No, Kyoung Tai, Choi, Kang‐Yell
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818757/
https://ncbi.nlm.nih.gov/pubmed/26941261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201505714
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