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Mitochondrial disorders in children: toward development of small‐molecule treatment strategies

This review presents our current understanding of the pathophysiology and potential treatment strategies with respect to mitochondrial disease in children. We focus on pathologies due to mutations in nuclear DNA‐encoded structural and assembly factors of the mitochondrial oxidative phosphorylation (...

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Bibliografische gegevens
Gepubliceerd in:EMBO Mol Med
Hoofdauteurs: Koopman, Werner JH, Beyrath, Julien, Fung, Cheuk‐Wing, Koene, Saskia, Rodenburg, Richard J, Willems, Peter HGM, Smeitink, Jan AM
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818752/
https://ncbi.nlm.nih.gov/pubmed/26951622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201506131
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