Nicotine Reduces Survival via Augmentation of Paracrine HGF-MET Signaling in the Pancreatic Cancer Microenvironment

PURPOSE: The relationship between smoking and pancreatic cancer (PC) biology, particularly in the context of the heterogeneous microenvironment, remains incompletely defined. We hypothesized that nicotine exposure would lead to the augmentation of paracrine growth factor signaling between tumor-asso...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Delitto, Daniel, Zhang, Dongyu, Han, Song, Black, Brian S., Knowlton, Andrea E., Vlada, Adrian C., Sarosi, George A., Behrns, Kevin E., Thomas, Ryan M., Lu, Xiaomin, Liu, Chen, George, Thomas J., Hughes, Steven J., Wallet, Shannon M., Trevino, Jose G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818664/
https://ncbi.nlm.nih.gov/pubmed/26667487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-1256
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