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A Phenotypic Compound Screening Assay for Lysosomal Storage Diseases

The lysosome is a vital cellular organelle that primarily functions as a recycling center for breaking down unwanted macromolecules through a series of hydrolases. Functional deficiencies in lysosomal proteins due to genetic mutations have been found in over 50 lysosomal storage diseases that exhibi...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :J Biomol Screen
Главные авторы: Xu, Miao, Liu, Ke, Swaroop, Manju, Sun, Wei, Dehdashti, Seameen J., McKew, John C., Zheng, Wei
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818652/
https://ncbi.nlm.nih.gov/pubmed/23983233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057113501197
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