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A Phenotypic Compound Screening Assay for Lysosomal Storage Diseases

The lysosome is a vital cellular organelle that primarily functions as a recycling center for breaking down unwanted macromolecules through a series of hydrolases. Functional deficiencies in lysosomal proteins due to genetic mutations have been found in over 50 lysosomal storage diseases that exhibi...

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Bibliografske podrobnosti
izdano v:J Biomol Screen
Main Authors: Xu, Miao, Liu, Ke, Swaroop, Manju, Sun, Wei, Dehdashti, Seameen J., McKew, John C., Zheng, Wei
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818652/
https://ncbi.nlm.nih.gov/pubmed/23983233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057113501197
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