Tyrosine phosphorylation is required for ligand-induced internalization of the antigen receptor on B lymphocytes.

The membrane immunoglobulin (mIg) receptor for antigen mediates signal transduction in B lymphocytes. Multivalent ligand induces several early activation events including an increase in intracellular calcium concentration, hydrolysis of phosphatidylinositol, and activation of protein kinase C. Most...

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Bibliographic Details
Main Authors: Puré, E, Tardelli, L
Format: Artigo
Language:Inglês
Published: 1992
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC48186/
https://ncbi.nlm.nih.gov/pubmed/1370346
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