Tyrosine phosphorylation is required for ligand-induced internalization of the antigen receptor on B lymphocytes.
The membrane immunoglobulin (mIg) receptor for antigen mediates signal transduction in B lymphocytes. Multivalent ligand induces several early activation events including an increase in intracellular calcium concentration, hydrolysis of phosphatidylinositol, and activation of protein kinase C. Most...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1992
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48186/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1370346/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.1.114 |
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