ARA290 Improves Insulin Release and Glucose Tolerance in Type 2 Diabetic Goto-Kakizaki Rats

Effects of ARA290 on glucose homeostasis were studied in type 2 diabetic Goto-Kakizaki (GK) rats. In GK rats receiving ARA290 daily for up to 4 wks, plasma glucose concentrations were lower after 3 and 4 wks, and hemoglobin A(1c) (Hb A(1c)) was reduced by ~20% without changes in whole body and hepat...

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Bibliographic Details
Published in:Mol Med
Main Authors: Muller, Carole, Yassin, Kamal, Li, Luo-Sheng, Palmblad, Magnus, Efendic, Suad, Berggren, Per-Olof, Cerami, Anthony, Brines, Michael, Östenson, Claes-Göran
Format: Artigo
Language:Inglês
Published: The Feinstein Institute Press 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818260/
https://ncbi.nlm.nih.gov/pubmed/26736179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2015.00267
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