BACE-1, PS-1 and sAPPβ Levels Are Increased in Plasma from Sporadic Inclusion Body Myositis Patients: Surrogate Biomarkers among Inflammatory Myopathies

Sporadic inclusion body myositis (sIBM) is a rare disease that is difficult to diagnose. Muscle biopsy provides three prominent pathological findings: inflammation, mitochondrial abnormalities and fibber degeneration, represented by the accumulation of protein depots constituted by β-amyloid peptide...

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Detalhes bibliográficos
Publicado no:Mol Med
Main Authors: Catalán-García, Marc, Garrabou, Glòria, Morén, Constanza, Guitart-Mampel, Mariona, Gonzalez-Casacuberta, Ingrid, Hernando, Adriana, Gallego-Escuredo, Jose Miquel, Yubero, Dèlia, Villarroya, Francesc, Montero, Raquel, O-Callaghan, Albert Selva, Cardellach, Francesc, Grau, Josep Maria
Formato: Artigo
Idioma:Inglês
Publicado em: The Feinstein Institute Press 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818257/
https://ncbi.nlm.nih.gov/pubmed/26552061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2015.00168
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