The transcription factor ATF2 promotes melanoma metastasis by suppressing protein fucosylation

Melanoma is one of the most lethal skin cancers worldwide, primarily because of its propensity to metastasize. Thus, the elucidation of mechanisms that govern metastatic propensity is urgently needed. We found that protein kinase Cε (PKCε)–mediated activation of activating transcription factor 2 (AT...

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Bibliografiske detaljer
Udgivet i:Sci Signal
Main Authors: Lau, Eric, Feng, Yongmei, Claps, Giuseppina, Fukuda, Michiko N., Perlina, Ally, Donn, Dylan, Jilaveanu, Lucia, Kluger, Harriet, Freeze, Hudson H., Ronai, Ze’ev A.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818095/
https://ncbi.nlm.nih.gov/pubmed/26645581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aac6479
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