Evaluation of RNA Amplification Methods to Improve DC Immunotherapy Antigen Presentation and Immune Response

Dendritic cells (DCs) transfected with total amplified tumor cell RNA have the potential to induce broad antitumor immune responses. However, analytical methods required for quantitatively assessing the integrity, fidelity, and functionality of the amplified RNA are lacking. We have developed a seri...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Slagter-Jäger, Jacoba G, Raney, Alexa, Lewis, Whitney E, DeBenedette, Mark A, Nicolette, Charles A, Tcherepanova, Irina Y
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Methods - Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817939/
https://ncbi.nlm.nih.gov/pubmed/23653155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2013.18
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