High Local Concentrations of Intradermal MSCs Restore Skin Integrity and Facilitate Wound Healing in Dystrophic Epidermolysis Bullosa

Dystrophic epidermolysis bullosa (DEB) is an incurable skin fragility disorder caused by mutations in the COL7A1 gene, coding for the anchoring fibril protein collagen VII (C7). Life-long mechanosensitivity of skin and mucosal surfaces is associated with large body surface erosions, chronic wounds,...

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Publicat a:Mol Ther
Autors principals: Kühl, Tobias, Mezger, Markus, Hausser, Ingrid, Handgretinger, Rupert, Bruckner-Tuderman, Leena, Nyström, Alexander
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817872/
https://ncbi.nlm.nih.gov/pubmed/25858020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.58
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