Local Delivery of Mutant CCL2 Protein-Reduced Orthopaedic Implant Wear Particle-Induced Osteolysis and Inflammation In Vivo

Total joint replacement (TJR) has been widely used as a standard treatment for late-stage arthritis. One challenge for long-term efficacy of TJR is the generation of ultra-high molecular weight polyethylene wear particles from the implant surface that activates an inflammatory cascade which may lead...

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Detalhes bibliográficos
Publicado no:J Orthop Res
Main Authors: Jiang, Xinyi, Sato, Taishi, Yao, Zhenyu, Keeney, Michael, Pajarinen, Jukka, Lin, Tzu-hua, Loi, Florence, Egashira, Kensuke, Goodman, Stuart, Yang, Fan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817847/
https://ncbi.nlm.nih.gov/pubmed/26174978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.22977
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