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Perfusion Pressure Is a Critical Determinant of the Intratumoral Extravasation of Oncolytic Viruses
Antitumor efficacy of oncolytic virotherapy is determined by the density and distribution of infectious centers within the tumor, which may be heavily influenced by the permeability and blood flow in tumor microvessels. Here, we investigated whether systemic perfusion pressure, a key driver of tumor...
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| Vydáno v: | Mol Ther |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4817823/ https://ncbi.nlm.nih.gov/pubmed/26647825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.219 |
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